Do not take ACOMPLIA

• if you are allergic (hypersensitive) to rimonabant, or any of the other ingredients of ACOMPLIA

• if you are breast-feeding.

Take special care with ACOMPLIA

Tell your doctor before you start to take this medicine:

• if you have impaired liver function

• if you have severely impaired renal function

• if you are currently being treated for epilepsy

• if you are less than 18 years of age. There is no information available on the use of ACOMPLIA in people under 18 years of age.

Taking other medicines

The activity of ACOMPLIA is increased by simultaneous use of some drugs (so-called CYP3A4 inhibitors) such as:

• itraconazole (antifungal medicine)

• ketaconazole (antifungal medicine)

• ritonavir (medicine for the treatment of HIV infections)

• telithromycin (antibiotic)

• clarithromycin (antibiotic)

• nefazodone (anti-depressor)

Please inform your doctor or pharmacist if you are taking or have recently taken the above mentioned medicines or any other medicines, including those obtained without a prescription such as St John’s wort, rifampicin (antibiotic), medicines for weight loss, medicines to improve blood lipids (fats), antidiabetes medicines and medicines to treat epilepsy (e.g. phenytoin, phenobarbital, carbamazepine) or depression.

Pregnancy and breast-feeding

ACOMPLIA should not be taken during pregnancy. Contact your doctornbsp; immediately if you become pregnant, think you might be pregnant or are planning to become pregnant while taking ACOMPLIA. Do not take this medicine when breast-feeding. Tell your doctor if you are breast-feeding or if you are planning to breast-feed your baby.

Driving and using machines

At the recommended dose, ACOMPLIA is not expected to reduce your ability to drive and use machines.

Important information about some of the ingredients of ACOMPLIA

ACOMPLIA tablets include lactose. If you are intolerant to some sugars, contact your doctor before taking this medicine.