Generic Acomplia / Zimulti (Slimona) is an anorectic anti-obesity drug (causes a reduction in appetite) Generic Acomplia / Zimulti (Slimona) works by blocking receptors called cannabinoid-1 receptors: CB1. CB1 receptors can be found in the brain, fat tissue, liver, digestive system and muscles. Overactivation of the CB1 receptors is associated with increased appetite, cravings for food and fat build-up. Generic Rimonabant (Slimona) blocks CB1 receptors and helps decrease appetite and reduces cravings for food. Generic Rimonabant (Slimona) may also reduce blood levels of “bad fats” and increase blood levels of “good fats” called HDL-cholesterol and. Generic Acomplia / Zimulti (Slimona) can also help people to quit smoking.